:root{--font-sans: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif;--bg-primary: #f8fafc;--bg-surface: #ffffff;--bg-elevated: #f1f5f9;--border-subtle: #e2e8f0;--border-strong: #cbd5e1;--text-primary: #0f172a;--text-secondary: #475569;--text-muted: #64748b;--color-primary: #2563eb;--color-primary-hover: #1d4ed8;--color-success: #059669;--color-success-bg: #ecfdf5;--color-warning: #d97706;--color-warning-bg: #fffbeb;--color-danger: #dc2626;--color-danger-bg: #fef2f2;--color-purple: #7c3aed;--color-purple-bg: #f5f3ff;--color-teal: #0d9488;--color-teal-bg: #f0fdfa;--shadow-sm: 0 1px 2px 0 rgba(0, 0, 0, .05);--shadow-md: 0 4px 6px -1px rgba(0, 0, 0, .1), 0 2px 4px -2px rgba(0, 0, 0, .1);--shadow-lg: 0 10px 15px -3px rgba(0, 0, 0, .1), 0 4px 6px -4px rgba(0, 0, 0, .1);--radius-sm: 6px;--radius-md: 8px;--radius-lg: 12px}*{box-sizing:border-box;margin:0;padding:0}body{font-family:var(--font-sans);background-color:var(--bg-primary);color:var(--text-primary);line-height:1.5;-webkit-font-smoothing:antialiased}button{font-family:inherit;cursor:pointer;border:none;background:none;font-size:.875rem;font-weight:500;transition:all .15s ease-in-out}input,textarea,select{font-family:inherit;font-size:.875rem;color:var(--text-primary);background:var(--bg-surface);border:1px solid var(--border-subtle);border-radius:var(--radius-sm);padding:.5rem .75rem;outline:none;transition:border-color .15s ease-in-out}input:focus,textarea:focus,select:focus{border-color:var(--color-primary);box-shadow:0 0 0 2px #2563eb33}.btn{display:inline-flex;align-items:center;justify-content:center;gap:.5rem;padding:.5rem 1rem;border-radius:var(--radius-sm);font-weight:600;cursor:pointer}.btn-primary{background-color:var(--color-primary);color:#fff}.btn-primary:hover{background-color:var(--color-primary-hover)}.btn-secondary{background-color:var(--bg-surface);border:1px solid var(--border-subtle);color:var(--text-primary)}.btn-secondary:hover{background-color:var(--bg-elevated)}.btn-success{background-color:var(--color-success);color:#fff}.btn-success:hover{background-color:#047857}.btn-danger-outline{border:1px solid var(--color-danger);color:var(--color-danger);background:transparent}.btn-danger-outline:hover{background-color:var(--color-danger-bg)}.badge{display:inline-flex;align-items:center;gap:.35rem;padding:.2rem .55rem;border-radius:9999px;font-size:.75rem;font-weight:600;text-transform:uppercase;letter-spacing:.025em}.badge-draft{background-color:var(--color-warning-bg);color:var(--color-warning);border:1px solid #fde68a}.badge-approved{background-color:var(--color-purple-bg);color:var(--color-purple);border:1px solid #ddd6fe}.badge-completed{background-color:var(--color-success-bg);color:var(--color-success);border:1px solid #a7f3d0}.badge-fee{background-color:#ecfeff;color:#0891b2;border:1px solid #a5f3fc}.badge-consent{background-color:#fdf2f8;color:#db2777;border:1px solid #fbcfe8}.badge-material{background-color:#fff7ed;color:#ea580c;border:1px solid #ffedd5}.badge-exam{background-color:#fefce8;color:#ca8a04;border:1px solid #fef08a}.badge-source{background-color:var(--bg-elevated);color:var(--text-secondary);border:1px solid var(--border-subtle)}.banner-evaluator{background:linear-gradient(135deg,#1e293b,#0f172a);color:#f8fafc;padding:.75rem 1.25rem;border-radius:var(--radius-md);margin-bottom:1rem;box-shadow:var(--shadow-md)}.banner-evaluator h3{font-size:.95rem;font-weight:700;margin-bottom:.25rem;display:flex;align-items:center;gap:.5rem;color:#38bdf8}.banner-evaluator p{font-size:.8rem;color:#cbd5e1;line-height:1.4}.banner-warning{background-color:var(--color-danger-bg);border:1px solid #fecaca;color:var(--color-danger);padding:.75rem 1rem;border-radius:var(--radius-sm);margin-bottom:1rem;font-size:.85rem}.banner-success{background-color:var(--color-success-bg);border:1px solid #a7f3d0;color:var(--color-success);padding:.75rem 1rem;border-radius:var(--radius-sm);margin-bottom:1rem;font-size:.85rem}.card{background:var(--bg-surface);border:1px solid var(--border-subtle);border-radius:var(--radius-md);padding:1.25rem;box-shadow:var(--shadow-sm);transition:box-shadow .15s ease-in-out}.card:hover{box-shadow:var(--shadow-md)}.modal-backdrop{position:fixed;top:0;right:0;bottom:0;left:0;background:#0f172a99;-webkit-backdrop-filter:blur(4px);backdrop-filter:blur(4px);display:flex;align-items:center;justify-content:center;z-index:50;padding:1rem}.modal-content{background:var(--bg-surface);border-radius:var(--radius-lg);max-width:650px;width:100%;max-height:90vh;overflow-y:auto;padding:1.5rem;box-shadow:var(--shadow-lg)}.app-container{max-width:1440px;margin:0 auto;padding:1.5rem 2rem}.grid-layout{display:grid;grid-template-columns:360px 1fr 340px;gap:1.5rem;align-items:start}@media(max-width:1200px){.grid-layout{grid-template-columns:340px 1fr}.audit-col{grid-column:span 2}}@media(max-width:800px){.grid-layout{grid-template-columns:1fr}.audit-col{grid-column:span 1}}@keyframes spin{0%{transform:rotate(0)}to{transform:rotate(360deg)}}.spin{animation:spin 1s linear infinite}